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Independent expert answers
on psychiatry and psychology

Biperiden-Counterreactions

Abstract: Other drugs, which can cause problems if taken at the same time as biperiden.

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Biperiden-Counterreactions

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Question(s): 
Written by: Petros Skapinakis, MD, MPH, PhD, lecturer of Psychiatry in the University of Ioannina Medical School, Greece.
Eva Gerasi<\/a>, postgraduate student in the Department of Psychiatry, University Hospital of Ioannina, Greece.
First version: 22 Jul 2008.
Latest revision: 29 Jul 2008.

What other drugs will affect Biperiden (Akineton)?

Answer:

Before taking this medication, patients should tell their doctor if they are taking:
  • a tricyclic antidepressant (TCA) (used to treat depression, pain, or obsessive-compulsive disorder) such as amitriptyline (Elavil, Endep), doxepin (Sinequan), or clomipramine (Anafranil);
  • other commonly used tricyclic antidepressants, including amoxapine (Asendin), desipramine (Norpramin), imipramine (Tofranil), nortriptyline (Pamelor), and protriptyline (Vivactil);
  • a phenothiazine (used to treat mania, schizophrenia, other psychiatric conditions, and nausea and vomiting) such as chlorpromazine (Thorazine), fluphenazine (Prolixin), perphenazine (Trilafon), mesoridazine (Serentil), thioridazine (Mellaril), promazine (Sparine), trifluoperazine (Stelazine), and others;
  • an antihistamine such as diphenhydramine (Benadryl, others), chlorpheniramine (Chlor-Trimeton, others), triprolidine (Actifed, others), brompheniramine (Dimetapp, others), clemastine (Tavist) and others (antihistamines are often found in prescription and over-the-counter cold, allergy, and sleep medicines);
  • quinidine (Quinora, Quinaglute, Quinidex, Cardioquin);
  • amantadine (Symmetrel);
  • digoxin (Lanoxin, Lanoxicaps); or
  • haloperidol (Haldol).

Drugs other than those listed here may also interact with biperiden. Therefore patients must first inform their doctor or pharmacist before taking any prescription or over-the-counter medicines, including herbal products.

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