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Monoamine Oxidase Inhibitors (MAOIs) - How They Work

Written by: Petros Skapinakis, MD, MPH, PhD, lecturer of Psychiatry in the University of Ioannina Medical School, Greece. Eva Gerasi, postgraduate student in the Department of Psychiatry, University Hospital of Ioannina, Greece.
First version: 22 Jul 2008. Latest version: 22 Jul 2008.


How do MAO inhibitors work?


How do MAOIs work?


These medications balance certain brain chemicals called neurotransmitters by reducing the amount of monoamine oxidase, the substance that breaks down the neurotransmitters. When these brain chemicals are in proper balance, the symptoms of depression are relieved.

MAO Inhibitors
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