Physical causes of this problem may originate in the hormonal regulation. The possibility of a-sexual persons is now being investigated. These are those who lack all interest in sexual contact, possibly because they lack a certain substance in their body.

There may be a specific aversion, for example to sperm, penises in erection, etc. Sexual violence, during childhood or at a later age, is often the cause of sexual aversion. Stress, alcohol and drug use, fear of pregnancy, depression and relation problems can cause aversion to sex.