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Monoamine oxidase inhibitors - Side-effects

Abstract: Do MAOIs have side-effects and which?

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Monoamine oxidase inhibitors - Side-effects

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Question(s): 
Written by: Petros Skapinakis, MD, MPH, PhD, lecturer of Psychiatry in the University of Ioannina Medical School, Greece. Eva Gerasi, postgraduate student in the Department of Psychiatry, University Hospital of Ioannina, Greece.
First version: 22 Jul 2008.
Latest revision: 29 Jul 2008.

Do MAOIs have side-effects and which?

Answer:

MAOIs interact with certain foods, drinks, and other medicines. Withdrawal symptoms may occur if MAOIs are stopped suddenly. Instead, the dose should be reduced gradually over about 4 weeks.

Common side effects include: dry mouth, insomnia, increased heart rate, drowsiness, blurred vision, appetite changes, muscle twitching and feelings of restlessness and loss of sexual desire or ability.

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